Research Article

Early postoperative hemodynamics and clinical outcomes of patients receiving freedom solo aortic calve replacement; the Asian Experience
  • Abid Amir
  • Hasrina Hassan
  • Raja Amin Raja Mokhtar
  • Sivakumar Krishnasamy
E J Cardiovasc Med 2013; 1: 1-7 DOI: 10.15511/ejcm.13.00101
Early period results for repair of complex thoracic aortic diseases with E-vita open stent graft
  • Mustafa Akbulut
  • Özgür Arslan
  • Adnan Ak
  • Serpil Taş
  • Davut Çekmecelioğlu
  • Arzu Dönmez
  • Mesut Şişmanoğlu
  • Altuğ Tuncer
E J Cardiovasc Med 2017; 5: 1-6 DOI: 10.15511/ejcm.17.00101
Hybrid coronary revascularization in beating heart coronary artery bypass; the results and review of the literature
  • Tuğra Gençpınar
  • Çağatay Bilen
  • Berke Özkan
  • Ebru Özpelit
  • Hasan Hepağuşlar
  • Kıvanç Metin
  • Hüdai Çatalyürek
E J Cardiovasc Med 2016; 4: 1-6 DOI: 10.15511/ejcm.16.00101
Increased risk of cardiovascular disease may be starting in childhood: 25 OH vitamin D levels in Turkish Children
  • Nilgün Işıksaçan
  • İsmail Bıyık
  • Pınar Kasapoğlu
  • Murat Koser
  • Fatma Nihan Turhan Caglar
  • Nursel Kocamaz
  • İbrahim Faruk Aktürk
E J Cardiovasc Med 2018; 6: 1-6 DOI: 10.15511/ejcm.18.00101
Increased Serum Elabela Level Related to NT-proBNP in Patients with Heart Failure
  • Atilla Bulut
  • Armağan Acele
  • Yurdaer Dönmez
  • Hilmi Erdem Sümbül
  • Mevlüt Koç
E J Cardiovasc Med 2020; 8: 1-9 DOI: 10.32596/ejcm.galenos.2020.11.059
Percutaneous transcatheter closure of patent foramen ovale in patients with paradoxical embolism
  • Francesco Pollice
  • Paolo Pollice
  • Lyan Jacob
E J Cardiovasc Med 2014; 2: 3-8 DOI: 10.15511/ejcm.14.00403
The Relationship Between N-Terminal Pro-Brain Natriuretic Peptide Level and Left Ventricular Metabolic Index in Patients with Heart Failure with Mildly Reduced Ejection Fraction
  • Mehmet Kış
  • Oktay Şenöz
  • Tuncay Güzel
E J Cardiovasc Med 2022; 10: 4-11 DOI: 10.32596/ejcm.galenos.2022.2021-12-063
Effectiveness of Off Pump CABG in impaired left ventricular function
  • Ihab Moursi
  • Mohamed Abd al aal
E J Cardiovasc Med 2016; 4: 7-12 DOI: 10.15511/ejcm.16.00107
Outcomes of with open and Seldinger-Guided Peripheral Cannulation Techniques in open heart surgery
  • Tuğra Gençpınar
  • Ceren Sayarer
  • Gökmen Akkaya
  • Öztekin Oto
E J Cardiovasc Med 2018; 6: 7-14 DOI: 10.15511/ejcm.18.00107
Self perception and quality of life of adolescents who had undergone open-heart surgery due to cyanotic congenital heart disease in their infancy
  • Cenk Eray Yıldız
  • Gürkan Çetin
  • Oğuzhan Zahmacıoğlu
  • Bülent Koca
  • Ayşe Güler Eroğlu
  • Selman Gökalp
  • Veysel Oktay
E J Cardiovasc Med 2013; 1: 8-14 DOI: 10.15511/ejcm.13.00108
Surgical treatment of patients with coronary heart disease and mild stenosis of the aortic valve
  • Anatoly Molochkov
  • Igor Zhbanov
  • Boris Shabalkin
  • Vadim Domnin
E J Cardiovasc Med 2014; 2: 9-14 DOI: 10.15511/ejcm.14.00409
A Research for Predictive Value of Hemogram Parameters at Late Term Arteriovenous Fistula Thrombosis Formation
  • Gökmen Akkaya
  • Çağatay Bilen
E J Cardiovasc Med 2019; 7: 9-15 DOI: 10.32596/ejcm.galenos.2019.00050
Outcomes of Cardiac Resynchronization Therapy in Heart Failure Patients and Effect of MAGGIC-HF Score on Prognosis
  • Gökay Nar
  • Sara Çetin
  • Gürsel Şen
  • Güven Günver
E J Cardiovasc Med 2021; 9: 9-18 DOI: 10.32596/ejcm.galenos.2020-11-064
Preoperative Correction of Tc-99-m-MIBI SPECT by F18-FDG Cardiac PET/CT for Myocardial Viability Before CABG
  • Süreyya Talay
  • Nahide Belgit Talay
E J Cardiovasc Med 2020; 8: 10-20 DOI: 10.32596/ejcm.galenos.2020.12.060
Association Between Insulin Resistance Estimated by Triglyceride Glucose Index and In-Stent Restenosis in Non-Diabetic Patients
  • Özge Kurmuş Ferik
  • Begüm Yetiş Sayın
  • Kürşat Akbuğa
  • Çağrı Zorlu
E J Cardiovasc Med 2022; 10: 12-17 DOI: 10.32596/ejcm.galenos.2022.2021-11-060
Sutureless aortic valve replacement: a theoretical analysis of the effective orifice area in comparison with stented valves
  • Igor Belluschi
  • Stefano Moriggia
  • Simona Nascimbene
  • Nicola Buzzatti
  • Ottavio Alfieri
E J Cardiovasc Med 2016; 4: 13-19 DOI: 10.15511/ejcm.16.00113
Clinical outcomes after drug-eluting stent implantation for unprotected left main coronary artery disease
  • Francesco Pollice
  • Paolo Pollice
  • Lyan Jacob
E J Cardiovasc Med 2013; 1: 15-19 DOI: 10.15511/ejcm.13.00115
Tranexamic Acid, a Low-cost and Practical Hemostatic Agent Against Diffuse Microvascular Bleeding Due to Coagulopathy in Heart Surgery
  • Kenan Abdurrahman Kara
  • Hakan Öntaş
E J Cardiovasc Med 2019; 7: 16-21 DOI: 10.32596/ejcm.galenos.2019.00003
The Role of Whole Blood Viscosity Estimated by De Simone’s Formula in Evaluation of Fractional Flow Reserve
  • Ahmet Akdi
  • Elif Hande Çetin
  • Özge Çakmak Karaaslan
  • Mehmet Akif Erdöl
  • Murat Oğuz Özilhan
  • Orhan Maden
  • Dursun Aras
E J Cardiovasc Med 2022; 10: 18-24 DOI: 10.32596/ejcm.galenos.2022.2021-11-059
Effects of Different Heart Positions During Off-pump Coronary Artery Bypass Surgery on Serum Ischemia Modified Albumin Level and Cardiac Output
  • Muhammet Bozgüney
  • Özgür Ersoy
  • İlker İnce
  • Rıfat Özmen
  • Zeki Temiztürk
  • Kanat Özışık
  • Uğursay Kızıltepe
E J Cardiovasc Med 2021; 9: 19-26 DOI: 10.32596/ejcm.galenos.2021-01-02
Experience with PTFE ‘Ecoflon’ (Russia) vascular grafts in surgery of aortoiliac lesions
  • Vladimir Alexandrovich Zelinskiy
  • Michail Viktorovich Melhikov
  • Aleksandr Emelyanovich Barsukov
  • Oleg Viktorovich Isaulov
  • Artur Urievich Apresyan
  • Sergey Anatolievich Vinnichuk
E J Cardiovasc Med 2013; 1: 20-25 DOI: 10.15511/ejcm.13.00120
The effect of enoxaparin on in vitro stimulated platelet aggregation by elective percutaneous coronary intervention patients
  • Ebru İpek Türkoğlu
  • Nazan Bitir
E J Cardiovasc Med 2017; 5: 21-26 DOI: 10.15511/ejcm.17.00221
Blood Pressure Control and Associated Factors in the Elderly Hypertensive Patients: Follow-up Data from the Special Hypertensive Outpatient Clinic
  • Umut Kocabaş
  • Filiz Özerkan Çakan
E J Cardiovasc Med 2020; 8: 21-27 DOI: 10.32596/ejcm.galenos.2020.07.041
Adherence of Rheumatic Heart Disease Patients to Secondary Prophylaxis and Main Reasons for Poor Adherence at Jimma Medical Center
  • Kenzu Mohammed
  • Wondu Reta Demissie
  • Moyeta Bariso Gare
E J Cardiovasc Med 2019; 7: 22-27 DOI: 10.32596/ejcm.galenos.2019.00004
Thoracoscopic sympathectomy using single port versus multiple ports as a treatment for palmar hyperhidrosis
  • Magdi Ibrahim Ahmad Muhammad
  • Abdulla Allam
E J Cardiovasc Med 2014; 2: 23-28 DOI: 10.15511/ejcm.14.00123
Long-Term Mortality of Nonischemic Seizures to Epilepsy After Open Heart Surgery
  • Kemal Karaarslan
  • Ayşe Gül Kunt
E J Cardiovasc Med 2022; 10: 25-31 DOI: 10.32596/ejcm.galenos.2022.2021-12-075
Hypertrophic obstructive cardiomyopathy and the cost of treatment
  • Azam Jan
  • S. Mumtaz Anwar Shah
  • Somaiya Rehman
  • Alessio Rungatscher
  • Naseer Ahmed
  • Giuseppe Faggian
E J Cardiovasc Med 2016; 4: 27-32 DOI: 10.15511/ejcm.16.00231
The Relationship Between Coronary Collateral Circulation and Visceral Fat
  • Adem Aktan
  • Tuncay Güzel
  • Mehmet Özbek
  • Muhammed Demir
  • Raif Kılıç
  • Bayram Arslan
  • Burhan Aslan
E J Cardiovasc Med 2021; 9: 27-38 DOI: 10.32596/ejcm.galenos.2021-01-05
Extra-corporeal Membrane Oxygenation Procedures on YouTube: What Practices Have Being Show
  • Tuğra Gençpınar
  • Çağatay Bilen
  • Serdar Bayrak
  • Gökmen Akkaya
  • Volkan Hancı
  • Sibel Büyükçoban
E J Cardiovasc Med 2019; 7: 28-35 DOI: 10.32596/ejcm.galenos.2019.00013
Long-term Efficacy and Safety of Cardioneuroablation in Patients with Vagally Mediated Bradyarrhythmias
  • Tümer Erdem Güler
  • Tolga Aksu
E J Cardiovasc Med 2020; 8: 28-34 DOI: 10.32596/ejcm.galenos.2020.02.07
New type of pump for the heart-lung bypass system
  • Nodar Gabriel Khodeli
  • Otar Sergei Shengelia
  • Zurab Apollon Chkhaidze
  • Djumber David Partsakhashvili
  • Tornike Jemal Sologashvili
E J Cardiovasc Med 2014; 2: 29-32 DOI: 10.15511/ejcm.14.00129
The significance of cardiac rhythm variability value assessment in partients with infective endocarditis
  • Natalia Feaktsistava
  • Volga Sujayeva
  • Swetlana Sudzhaeva
E J Cardiovasc Med 2013; 1: 32-35 DOI: 10.15511/ejcm.13.00232
Relationship Between Ambulatory Blood Pressure Variability and Atherogenic Index of Plasma
  • Serkan Asil
  • Veysel Özgür Barış
  • Özkan Eravcı
  • Hatice Taşkan
  • Murat Çelik
  • Uygar Çağdaş Yüksel
E J Cardiovasc Med 2022; 10: 32-39 DOI: 10.32596/ejcm.galenos.2022.2022-02-016
Echocardiographic findings among children with pectus excavatum
  • Esra Akyüz Özkan
  • Hashem E. Khosroshahi
  • Mahmut Kılıç
  • Bayram Metin
  • Halil İ. Serin
E J Cardiovasc Med 2016; 4: 33-40 DOI: 10.15511/ejcm.16.00237
Our Experience in Anesthesia Management in Operations for Congenital Pediatric Cardiac Diseases
  • Buket Özyaprak
  • Filiz Ata
  • Mürüvvet Dayıoğlu
  • Kurtbey Anarat
  • Mehmet Kaydul
  • Yılmaz Apaydın
  • Mehmet Gamlı
  • Ümran Karaca
  • Serkan Seçici
  • Cüneyt Eriş
  • Yusuf Ata
  • Nail Kahraman
  • Gönül Erkan
  • Ahmet Eroğlu
E J Cardiovasc Med 2020; 8: 35-44 DOI: 10.32596/ejcm.galenos.2020.02.05
Percutaneous coronary revascularization in diabetics
  • Francesco Pollice
  • Paolo Pollice
  • Lyan Jacob
E J Cardiovasc Med 2013; 1: 36-44 DOI: 10.15511/ejcm.13.00236
Retrospective Evaluation of the First 150 Patients with Vascular Surgery in A New Cardiovascular Surgery Clinic
  • Mazlum Şahin
  • Fatma Tuğba İlal Mert
  • Gökay Altaylı
E J Cardiovasc Med 2018; 6: 36-41 DOI: 10.15511/ejcm.18.00236
Association Between Microalbuminuria and Pulse Pressure Among Patients with Isolated Systolic and Diastolic Hypertension
  • Şenol Coşkun
  • Jale Cordan
  • Ertuğrul Mehmetoğlu
  • Saim Sağ
  • Dilek Yeşilbursa
  • Osman Akın Serdar
  • Sümeyye Güllülü
  • Ali Aydınlar
E J Cardiovasc Med 2021; 9: 39-48 DOI: 10.32596/ejcm.galenos.2020-10-056
The Tactics of Safe Removal of Heart Myxomas; The Experience of 796 Operations
  • Rostyslav Vitovskiy
  • Volodymyr Isaienko
  • Olexandr Pishchurin
  • Volodymyr Onishchenko
  • Igor Martyshchenko
  • Dmitriy Dyadyun
E J Cardiovasc Med 2018; 6: 42-45 DOI: 10.15511/ejcm.18.00242
Comparison between two sternum closing techniques by median sternotomy during open cardiac surgery
  • Kenan Abdurrahman Kara
  • Zafer Erk
  • Aytuğ Koçyiğit
  • Şenol Gülmen
  • Ahmet Öcal
  • Hüseyin Okutan
E J Cardiovasc Med 2017; 5: 44-49 DOI: 10.15511/ejcm.17.00344
A Comparison of NBCA and RFA in Treating Varicose Veins in the Same Patient
  • Orhan Bozoğlan
E J Cardiovasc Med 2020; 8: 45-50 DOI: 10.32596/ejcm.galenos.2020.02.09
Synchronous off-pump coronary artery bypass grafting and carotid endarterectomy (an initial experience)
  • Abdusalom Abdurakhmanov
  • Mustapha Obeid
  • Oybek Mashrapov
  • Nodirjon Rakhimov
  • Ulugbek Ganiev
  • Nodirbek Sultanov
  • Bakhtiyor Khamidov
  • Natalia Dadamyantz
E J Cardiovasc Med 2018; 6: 46-51 DOI: 10.15511/ejcm.18.00246
Patent Foramen Ovale: A Practical and Imaging Based Morphological Classification
  • Begüm Yetiş Sayın
  • Ali Oto
E J Cardiovasc Med 2022; 10: 47-56 DOI: 10.32596/ejcm.galenos.2022.2022-05-032
Need for hypogastric artery preservation in endovascular repair for aorto – Iliac Aneurysms
  • Rocco Giudice
  • Ottavia Borghese
  • Raimondo Grossi
  • Carlo Coscarella
  • Giorgio Sbenaglia
  • Silvana Pirillo
  • Massimo Danese
  • Mario Albertucci
E J Cardiovasc Med 2016; 4: 49-55 DOI: 10.15511/ejcm.16.00349
Are Atrial High-rate Episodes a Kind of Sympathetic Overactivity in Patient with Permanent Pacemaker?
  • Ömer Çağlar Yılmaz
E J Cardiovasc Med 2021; 9: 49-52 DOI: 10.32596/ejcm.galenos.2021-01-07
The effect of benfothiamin and vitamın D in ischemia / Reperfusion model of rat skeletal muscle
  • Özlem Keskin
  • Mehmet Sipahi
  • Vehbi Yavuz Tokgöz
  • Selçuk Takır
  • Gülname Fındık Güvendi
E J Cardiovasc Med 2018; 6: 52-59 DOI: 10.15511/ejcm.18.00252
Association of SYNTAX Score with PATIMA Index, Carotid Intima- and Extra- Media Thicknesses
  • Mehmet Cosgun
  • Zeliha Cosgun
  • Yılmaz Güneş
  • İsa Sincer
  • Emrah Erdal
  • Aslı Kurtar Mansıroğlu
  • Mehmet İnanır
E J Cardiovasc Med 2021; 9: 53-60 DOI: 10.32596/ejcm.galenos.2021-01-09
Aortic surgery cost and outcome at teaching vs. non-teaching hospitals
  • Azam Jan
  • Naseer Ahmed
  • S. Mumtaz Anwar Shah
  • Somiya Rehman
  • Alessio Rungatscher
  • Giuseppe Faggian
E J Cardiovasc Med 2016; 4: 56-62 DOI: 10.15511/ejcm.16.00380
Diffusion-weighted Imaging Versus Doppler Ultrasound in the Diagnosis of Calf Deep Vein Thrombosis
  • Zeynep Nilüfer Tekin
  • Ali Türk
  • Zeynep Bilgi
  • Özlem Barutçu
E J Cardiovasc Med 2022; 10: 57-63 DOI: 10.32596/ejcm.galenos.2022.2022-03-022
Serum Presepsin Levels in Patients with Decompensated Heart Failure
  • İsmail Bıyık
  • Fatma Nihan Turhan Çağlar
  • Nilgün Işıksaçan
  • Mustafa Hakan Şahin
  • Dilay Karabulut
  • Fahrettin Katkat
  • Faruk Aktürk
E J Cardiovasc Med 2018; 6: 60-67 DOI: 10.15511/ejcm.18.00260
Evaluation of Reintervention Frequency in Patients Undergoing Interventional and/or Surgical Treatment for Aortic Coarctation
  • Cansu Özdemiral
  • Timur Meşe
  • Murat Muhtar Yılmazer
  • Mustafa Karaçelik
  • Engin Gerçeker
  • Cüneyt Zihni
E J Cardiovasc Med 2021; 9: 61-69 DOI: 10.32596/ejcm.galenos.2020-12-067
Red Cell Distribution Width Predicts the Left Ventricular Reverse Remodeling After ST Segment Elevation Myocardial Infarction Undergone Primary Percutaneous Coronary Intervention
  • Pınar Demir Gündoğmuş
  • Kamuran Kalkan
  • Remziye Doğan
  • Abdulkadir Uslu
  • Enbiya Aksakal
E J Cardiovasc Med 2020; 8: 63-71 DOI: 10.32596/ejcm.galenos.2020.01.01
Comparison of Ischemia-modified Albumin and Exercise Stress Test in Stable Angina Pectoris
  • Murat Özmen
  • Şule Karakelleoğlu
  • İsa Ardahanlı
E J Cardiovasc Med 2022; 10: 64-71 DOI: 10.32596/ejcm.galenos.2022.2021-12-069
Is There A Correlation Between Left Atrium Diameter and NT-ProBNP Levels in Resistant Hypertension?
  • Ebru İpek Türkoğlu
  • Eser Şekercioğlu
E J Cardiovasc Med 2019; 7: 66-71 DOI: 10.32596/ejcm.galenos.2019.00009
Correlations between hematological indicators and other known markers in acute coronary syndromes
  • Mehmet Ertürk
  • Fatma N. Turhan Caglar
  • İsmail Bıyık
  • Nilgün Işıksaçan
  • Serkan Yazan
  • Mehmet Rıfat Yıldırım
  • Ömer Faruk Baycan
  • Begüm Özalp
  • Hüseyin Karakurt
E J Cardiovasc Med 2017; 5: 67-74 DOI: 10.15511/ejcm.17.00467
The Relationship Between Physical Activity Status and Dietary Habits with the Risk of Cardiovascular Diseases
  • Asim Alaaeldin Osman
  • Zahra Mustafa Abumanga
E J Cardiovasc Med 2019; 7: 72-78 DOI: 10.32596/ejcm.galenos.2019.00008
Atrial Fibrillation, Heart Failure with Impaired Ejection Fraction and Natriuretic Peptides
  • Ebru İpek Türkoğlu
  • Emine Çiğdem Kırçiçeği Çiçekdağ
E J Cardiovasc Med 2020; 8: 72-77 DOI: 10.32596/ejcm.galenos.2020.03.014
Effect of Admission Hyperglycemia on Mortality in Diabetic and Non-diabetic Geriatric Patients with Non-ST-segment Elevation Myocardial Infarction
  • Pınar Demir Gündoğmuş
  • Ümran Keskin
E J Cardiovasc Med 2022; 10: 72-82 DOI: 10.32596/ejcm.galenos.2022.2021-12-072
High Triglyceride Glucose Index Does Not Show the Presence and Severity of Coronary Artery Disease: A Single-Center Study
  • Sara Çetin Şanlıalp
  • Gökay Nar
  • Gürsel Şen
  • Mehmet Güven Günver
  • Musa Şanlıalp
E J Cardiovasc Med 2021; 9: 76-82 DOI: 10.32596/ejcm.galenos.2021-01-03
Severe calcific constrictive pericardiectomy operation: ‘Hearts of stone’
  • Tuğra Gençpınar
  • Çağatay Bilen
  • Gökmen Akkaya
  • Hasan Hepağuşlar
  • Kıvanç Metin
  • Hudai Çatalyürek
  • Öztekin Oto
E J Cardiovasc Med 2016; 4: 77-82 DOI: 10.15511/ejcm.16.04077
The Obesity Paradox Existing in Idiopathic Pulmonary Arterial Hypertension
  • Bihter Şentürk
  • Bahri Akdeniz
  • Ebru Özpelit
  • Mehmet Birhan Yılmaz
  • Buse Özcan Kahraman
  • Dilek Sezgin
  • Kemal Can Tertemiz
  • Can Sevinç
E J Cardiovasc Med 2020; 8: 78-84 DOI: 10.32596/ejcm.galenos.2020.02.011
Cardiopulmonary Bypass Management Using High-volume Continuous Hemofiltration in Patients with Comorbidities
  • Georgiy Plotnikov
  • Vadim Popov
  • Vladimir Chagirev
  • Giorgiy Edzhibiya
  • Egor Malyshenko
  • Amiran Revishvili
E J Cardiovasc Med 2019; 7: 79-83 DOI: 10.32596/ejcm.galenos.2019.00019
Importance of Renal Dysfunction in the Mortality of Acute Coronary Syndrome Patients
  • Maria Eduarda Seabra Halmeira
  • Nathalia R. Sousa
  • Camila N. Santana
  • Mário S. Rocha
E J Cardiovasc Med 2016; 4: 83-88 DOI: 10.15511/ejcm.16.04098
Initial Experience Using AutoMark in Atrial Fibrillation Ablation
  • Krasimir R. Dzhinsov
  • Tosho L. Balabanski
E J Cardiovasc Med 2018; 6: 83-88 DOI: 10.32596/ejcm.18.00383
Telemedicine in Cardiology Outpatient Clinic: First Experience from a Tertiary Medical Center During the COVID-19 Pandemic
  • Elton Soydan
  • Meral Kayıkçıoğlu
  • Mehdi Zoghi
E J Cardiovasc Med 2021; 9: 83-93 DOI: 10.32596/ejcm.galenos.2021-01-08
Cystatin C and Its Temporal Change May Predict Development and Recovery of Cardio-renal Syndrome Type 1 in Acute Heart Failure
  • Eser Açıkgöz
  • Sadık Kadri Açıkgöz
  • Murat Oğuz Özilhan
  • Mustafa Candemir
  • Gökhan Gökalp
  • Özge Çakmak Karaaslan
  • Serdar Gökhan Nurkoç
  • Ajar Koçak
  • Gülbahar Özlem
  • Hüseyin Murat Özdemir
E J Cardiovasc Med 2022; 10: 83-92 DOI: 10.32596/ejcm.galenos.2022.2022-01-01
The Protective Role of Resveratrol on Diabetic Cardiomyopathy in Streptozocin Induced Diabetic Rats
  • İsmail Polat Canbolat
  • Türker Çavuşoğlu
  • Gürkan Yiğittürk
  • Utku Ateş
  • Oytun Erbaş
E J Cardiovasc Med 2019; 7: 84-88 DOI: 10.32596/ejcm.galenos.2019.00023
Noncompaction Phenotype, But What is Cause and is the Diagnosis Correct?
  • Onur Akhan
E J Cardiovasc Med 2020; 8: 85-90 DOI: 10.32596/ejcm.galenos.2020.03.013